DAO Deficiency

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clinica britania femalefocusonline july22 2I suffer with migraines and bloating on a regular basis and am becoming increasingly concerned. What could be the cause of this?


Consult with your GP as DAO Deficiency could be the root of the problem. This occurs when there is an alteration in the metabolism of food histamine that appears when the DAO enzyme activity is low. In other words, when for some reason there is a significant deficiency in the functional activity of the main enzyme in the metabolism of histamine.
The imbalance between ingested histamine and the histamine released from the histamine storage cells, leads to histamine accumulation in the plasma of the blood, triggering the occurrence of adverse effects on health.
clinica britania femalefocusonline july22 1In healthy people, histamine taken with food is degraded quickly by Diamine Oxidase (DAO) enzyme, but people with low functional DAO activity have the risk of suffering histamine intolerance.
Unlike food allergy, the occurrence of symptoms is not linked to the intake of specific food; not only can it be related to a wide variety of food with different histamine contents, but symptoms can also occur even after the ingestion of products with low histamine levels.
Contact your GP for further investigations if you are suffering from:
• Migraine or vascular headaches.
• Constipation, diarrhoea, flatulence, or regular bloating.
• Dermatological disorders such as dry skin, atopy, or psoriasis.
• Fibromyalgia and Chronic fatigue.

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